A wine region that spreads along the border with Austria in the vicinity of an ancient wine town Znojmo that played an important role in Czech history and whose name has given the name to the whole wine region.

The Znojmo wine region lies in the rain shadow and on the foothills of the Bohemia-Moravian Highland, whose stony soils are excellent for the cultivation of Riesling, Grüner Veltliner, and in certain parts and wine villages (Dolni Kounice even) for red varieties such as Blaufränkisch and Pinot Noir.